News List
Ni-Catalyzed Traceless, Directed C3-Selective C–H Borylation of Indoles
Jul 17, 2020
A highly efficient and general protocol for traceless, directed C3-selective C–H borylation of indoles with [Ni(IMes)2]
Global drug developments
Jul 3, 2020
Drug name: umbralisibCAS: 1532533-67-7Target and IC50: PI3Kδ, 22.2 nMIndications: chronic lymphocytic leukemiaDevelopmen
Visible-Light-Driven C4-Selective Alkylation of Pyridinium Derivatives with Alkyl Bromides
Jun 19, 2020
Reported herein is a general strategy for the photochemical cross-coupling between N-amidopyridinium salts and various a
Deuteriodifluoromethylation and gem ‐Difluoroalkenylation of Aldehydes Using ClCF2H in Continuous Flow
Jun 19, 2020
The deuteriodifluoromethyl group (CF2D) represents a challenging functional group due to difficult deuterium incorporati